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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXO6 All Species: 27.58
Human Site: S445 Identified Species: 60.67
UniProt: A8MYZ6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MYZ6 XP_002342143.1 492 50595 S445 D L D M F S G S L E C D V E S
Chimpanzee Pan troglodytes XP_001135016 505 53494 S462 T P P T E A A S Q D R M P Q D
Rhesus Macaque Macaca mulatta XP_001086081 435 46581 C384 L D S H Q P G C R L C P L T A
Dog Lupus familis XP_549066 509 54008 A464 V L T P A T E A A S Q D R M P
Cat Felis silvestris
Mouse Mus musculus Q70KY4 559 57577 S512 D L D M F S G S L E C D V E S
Rat Rattus norvegicus XP_001057233 559 57408 S512 D L D M F S G S L E C D V E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511165 628 67175 S574 D L D I F N G S L E C D M E S
Chicken Gallus gallus XP_001234496 703 74609 S649 D L D I F N G S L E C D M E S
Frog Xenopus laevis Q6EUW1 657 70366 S604 D L D I F N G S L E C D M E T
Zebra Danio Brachydanio rerio NP_001128604 711 77678 S651 E M D V H Q S S L D C D V E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95V55 613 67394 N473 L E N F P V G N L E C N V E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.2 67.2 38.1 N.A. 84.7 84.9 N.A. 36.1 36.1 35.7 37.4 N.A. 29.2 N.A. N.A. N.A.
Protein Similarity: 100 48.7 71.1 48.9 N.A. 85.8 86 N.A. 47.4 46.9 46.4 46.9 N.A. 38.8 N.A. N.A. N.A.
P-Site Identity: 100 6.6 13.3 13.3 N.A. 100 100 N.A. 80 80 73.3 53.3 N.A. 40 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 26.6 26.6 N.A. 100 100 N.A. 100 100 100 80 N.A. 60 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 10 10 10 10 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 82 0 0 0 0 % C
% Asp: 55 10 64 0 0 0 0 0 0 19 0 73 0 0 10 % D
% Glu: 10 10 0 0 10 0 10 0 0 64 0 0 0 73 10 % E
% Phe: 0 0 0 10 55 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 73 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 28 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 19 64 0 0 0 0 0 0 73 10 0 0 10 0 0 % L
% Met: 0 10 0 28 0 0 0 0 0 0 0 10 28 10 0 % M
% Asn: 0 0 10 0 0 28 0 10 0 0 0 10 0 0 0 % N
% Pro: 0 10 10 10 10 10 0 0 0 0 0 10 10 0 10 % P
% Gln: 0 0 0 0 10 10 0 0 10 0 10 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 10 0 10 0 0 % R
% Ser: 0 0 10 0 0 28 10 73 0 10 0 0 0 0 55 % S
% Thr: 10 0 10 10 0 10 0 0 0 0 0 0 0 10 10 % T
% Val: 10 0 0 10 0 10 0 0 0 0 0 0 46 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _